Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis

Hyperactivation of sterol regulatory element binding protein 1c (SREBP‐1c), which transcriptionally induces expression of enzymes responsible for de novo lipogenesis and triglyceride (TG) formation, is implicated in nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) pathoge...

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Detalles Bibliográficos
Autores principales: Swiatek, Wojciech, Parnell, K. Mark, Nickols, G. Allen, Scharschmidt, Bruce F., Rutter, Jared
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193131/
https://www.ncbi.nlm.nih.gov/pubmed/32363320
http://dx.doi.org/10.1002/hep4.1498

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