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Pyruvate alleviates high glucose‐induced endoplasmic reticulum stress and apoptosis in HK‐2 cells

Endoplasmic reticulum (ER) stress plays a critical role in the development of diabetic nephropathy (DN). We previously demonstrated that pyruvate (Pyr)‐enriched oral rehydration solution improved glucometabolic disorders and ameliorated DN outcome in db/db mice. Here, we investigated the effects of...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao Meng, Wang, Yi Zhen, Tong, Jin Dong, Ning, Xu Chao, Zhou, Fang Qiang, Yang, Xiu Hong, Jin, Hui Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193158/
https://www.ncbi.nlm.nih.gov/pubmed/32150786
http://dx.doi.org/10.1002/2211-5463.12834

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