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Interferon‐γ‐induced HLA Class II expression on endothelial cells is decreased by inhibition of mTOR and HMG‐CoA reductase

In organ transplantation, donor‐specific HLA antibody (DSA) is considered a major cause of graft rejection. Because DSA targets primarily donor‐specific human leukocyte antigen (HLA) expressed on graft endothelial cells, the prevention of its expression is a possible strategy for avoiding or salvagi...

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Detalles Bibliográficos
Autores principales: Maenaka, Akihiro, Kenta, Iwasaki, Ota, Akinobu, Miwa, Yuko, Ohashi, Wataru, Horimi, Kosei, Matsuoka, Yutaka, Ohnishi, Masafumi, Uchida, Kazuharu, Kobayashi, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193171/
https://www.ncbi.nlm.nih.gov/pubmed/32237049
http://dx.doi.org/10.1002/2211-5463.12854