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Prediction of the Network Pharmacology-Based Mechanism for Attenuation of Atherosclerosis in Apolipoprotein E Knockout Mice by Panax notoginseng Saponins

This study investigated whether Panax notoginseng saponins (PNS) reduced atherosclerotic lesion formation in apolipoprotein E knockout (ApoE-KO) mice and illustrated the potential mechanism for a network pharmacology approach. Pharmacodynamics studies on ApoE-KO mice with atherosclerosis (AS) showed...

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Detalles Bibliográficos
Autores principales: Long, Linzi, Yu, Zikai, Qu, Hua, Wang, Ning, Guo, Ming, Zhou, Xuezhong, Fu, Changgeng, Gao, Zhuye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193284/
https://www.ncbi.nlm.nih.gov/pubmed/32382308
http://dx.doi.org/10.1155/2020/8574702