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Pharmacological prevention of surgery-accelerated metastasis in an animal model of osteosarcoma
BACKGROUND: Osteosarcoma is a highly metastatic primary bone tumor that predominantly affects adolescents and young adults. A mainstay of treatment in osteosarcoma is removal of the primary tumor. However, surgical excision itself has been implicated in promoting tumor growth and metastasis, an effe...
Autores principales: | Kallis, Michelle P., Maloney, Caroline, Blank, Brandon, Soffer, Samuel Z., Symons, Marc, Steinberg, Bettie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193344/ https://www.ncbi.nlm.nih.gov/pubmed/32354335 http://dx.doi.org/10.1186/s12967-020-02348-2 |
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