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Sensitive detection methods are key to identify secondary EGFR c.2369C>T p.(Thr790Met) in non-small cell lung cancer tissue samples
BACKGROUND: Correct identification of the EGFR c.2369C>T p.(Thr790Met) variant is key to decide on a targeted therapeutic strategy for patients with acquired EGFR TKI resistance in non-small cell lung cancer. The aim of this study was to evaluate the correct detection of this variant in 12 tumor...
Autores principales: | Keppens, Cleo, Dequeker, Elisabeth M. C., Rouleau, Etienne, ’t Hart, Nils, Bubendorf, Lukas, Dufraing, Kelly, Garrec, Céline, Guéguen, Paul, Lamy, Aude, Marchetti, Antonio, Pauwels, Patrick, Ryska, Ales, Tack, Véronique, Tornillo, Luigi, Van Casteren, Kaat, von der Thüsen, Jan H., Zwaenepoel, Karen, Lissenberg-Witte, Birgit, Thunnissen, Erik, Schuuring, Ed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193365/ https://www.ncbi.nlm.nih.gov/pubmed/32357863 http://dx.doi.org/10.1186/s12885-020-06831-3 |
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