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The anti-neoplastic effect of doxycycline in osteosarcoma as a metalloproteinase (MMP) inhibitor: a systematic review

BACKGROUND: Osteosarcoma is a very aggressive primary bone tumour, affecting mainly young populations. Most cases diagnosed have distant macro- and micro-metastases at the time of diagnosis. Surgical resection with neoadjuvant and adjuvant therapies improves the overall and disease-free survival of...

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Detalles Bibliográficos
Autores principales: Hadjimichael, Argyris C., Foukas, Athanasios F., Savvidou, Olga D., Mavrogenis, Andreas F., Psyrri, Amanda K., Papagelopoulos, Panayiotis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193389/
https://www.ncbi.nlm.nih.gov/pubmed/32377334
http://dx.doi.org/10.1186/s13569-020-00128-6

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