Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer

BACKGROUND: Altered signaling pathways typify breast cancer and serve as direct inputs to steroid hormone receptor sensors. We previously reported that phospho-Ser134-GR (pS134-GR) species are elevated in triple-negative breast cancer (TNBC) and cooperate with hypoxia-inducible factors, providing a...

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Detalles Bibliográficos
Autores principales: Perez Kerkvliet, Carlos, Dwyer, Amy R., Diep, Caroline H., Oakley, Robert H., Liddle, Christopher, Cidlowski, John A., Lange, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193415/
https://www.ncbi.nlm.nih.gov/pubmed/32357907
http://dx.doi.org/10.1186/s13058-020-01277-8

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