The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations

The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics. In addition, we compared the fluvastatin pharmacokinetics differences between extended-release (ER) 80 mg tablet and immediate-release (IR) 40 mg capsule in terms of drug metabolis...

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Detalles Bibliográficos
Autores principales: Xiang, Qian, Wu, Weidang, Zhao, Nan, Li, Chuan, Xu, Junyu, Ma, Lingyue, Zhang, Xiaodan, Xie, Qiufen, Zhang, Zhuo, Wang, Jiancheng, Xu, Weiren, Zhao, Xia, Cui, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193447/
https://www.ncbi.nlm.nih.gov/pubmed/32373204
http://dx.doi.org/10.1016/j.ajps.2019.06.002

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