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Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation

Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platelet-derived extracellular vesicles which rapidly and...

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Detalles Bibliográficos
Autores principales: Chimen, Myriam, Evryviadou, Aigli, Box, Clare L., Harrison, Matthew J., Hazeldine, Jon, Dib, Lea H., Kuravi, Sahithi J., Payne, Holly, Price, Joshua M.J., Kavanagh, Dean, Iqbal, Asif J., Lax, Sian, Kalia, Neena, Brill, Alex, Thomas, Steve G., Belli, Antonio, Crombie, Nicholas, Adams, Rachel A., Evans, Shelley-Ann, Deckmyn, Hans, Lord, Janet M., Harrison, Paul, Watson, Steve P., Nash, Gerard B., Rainger, G. Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193470/
https://www.ncbi.nlm.nih.gov/pubmed/31467123
http://dx.doi.org/10.3324/haematol.2018.215145