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Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation
Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platelet-derived extracellular vesicles which rapidly and...
Autores principales: | Chimen, Myriam, Evryviadou, Aigli, Box, Clare L., Harrison, Matthew J., Hazeldine, Jon, Dib, Lea H., Kuravi, Sahithi J., Payne, Holly, Price, Joshua M.J., Kavanagh, Dean, Iqbal, Asif J., Lax, Sian, Kalia, Neena, Brill, Alex, Thomas, Steve G., Belli, Antonio, Crombie, Nicholas, Adams, Rachel A., Evans, Shelley-Ann, Deckmyn, Hans, Lord, Janet M., Harrison, Paul, Watson, Steve P., Nash, Gerard B., Rainger, G. Ed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193470/ https://www.ncbi.nlm.nih.gov/pubmed/31467123 http://dx.doi.org/10.3324/haematol.2018.215145 |
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