An increase in MYC copy number has a progressive negative prognostic impact in patients with diffuse large B-cell and high-grade lymphoma, who may benefit from intensified treatment regimens

MYC translocations, a hallmark of Burkitt lymphoma, occur in 5-15% of diffuse large B-cell lymphoma, and have a negative prognostic impact. Numerical aberrations of MYC have also been detected in these patients, but their incidence and prognostic role are still controversial. We analyzed the clinica...

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Detalles Bibliográficos
Autores principales: Schieppati, Francesca, Balzarini, Piera, Fisogni, Simona, Re, Alessandro, Pagani, Chiara, Bianchetti, Nicola, Micheli, Lorenzo, Passi, Angela, Ferrari, Samantha, Maifredi, Adriana, Bottelli, Chiara, Leopaldo, Rossella, Pellegrini, Vilma, Facchetti, Fabio, Rossi, Giuseppe, Tucci, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193495/
https://www.ncbi.nlm.nih.gov/pubmed/31399522
http://dx.doi.org/10.3324/haematol.2019.223891

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