Cargando…
Dynamin 2 is required for GPVI signaling and platelet hemostatic function in mice
Receptor-mediated endocytosis, which contributes to a wide range of cellular functions, including receptor signaling, cell adhesion, and migration, requires endocytic vesicle release by the large GTPase dynamin 2. Here, the role of dynamin 2 was investigated in platelet hemostatic function using bot...
Autores principales: | Eaton, Nathan, Drew, Caleb, Wieser, Jon, Munday, Adam D., Falet, Hervé |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193499/ https://www.ncbi.nlm.nih.gov/pubmed/31296575 http://dx.doi.org/10.3324/haematol.2019.218644 |
Ejemplares similares
-
Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets
por: Poulter, N. S., et al.
Publicado: (2017) -
Rac Inhibition Causes Impaired GPVI Signalling in Human Platelets through GPVI Shedding and Reduction in PLCγ2 Phosphorylation
por: Neagoe, Raluca A. I., et al.
Publicado: (2022) -
Differential Inhibition of Human Atherosclerotic Plaque–Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies
por: Jamasbi, Janina, et al.
Publicado: (2015) -
mTOR regulates GPVI-mediated platelet activation
por: Wang, Longsheng, et al.
Publicado: (2021) -
GPVI expression is linked to platelet size, age, and reactivity
por: Veninga, Alicia, et al.
Publicado: (2022)