Cargando…
Eomes identifies thymic precursors of self-specific memory-phenotype CD8(+) T cells
Unprimed mice harbor a substantial population of "memory-phenotype" CD8(+) T cells (CD8-MP cells) that exhibit hallmarks of activation and innate-like functional properties. Due to the lack of faithful markers to distinguish CD8-MP cells from bona fide CD8(+) memory T cells, the developmen...
Autores principales: | Miller, Christine H., Klawon, David E.J., Zeng, Sharon, Lee, Victoria, Socci, Nicholas D., Savage, Peter A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193531/ https://www.ncbi.nlm.nih.gov/pubmed/32284593 http://dx.doi.org/10.1038/s41590-020-0653-1 |
Ejemplares similares
-
Proinflammatory IFNγ Is Produced by but Not Required for the Generation of Eomes(+) Thymic Innate CD8 T Cells
por: Won, Hee Yeun, et al.
Publicado: (2023) -
T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection
por: Buggert, Marcus, et al.
Publicado: (2014) -
Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity
por: Kavazović, Inga, et al.
Publicado: (2020) -
TGF-β and Eomes control the homeostasis of CD8(+) regulatory T cells
por: Mishra, Shruti, et al.
Publicado: (2020) -
High Levels of Eomes Promote Exhaustion of Anti-tumor CD8(+) T Cells
por: Li, Jing, et al.
Publicado: (2018)