DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres

Homologous recombination between repetitive sequences can lead to gross chromosomal rearrangements (GCRs). At fission yeast centromeres, Rad51-dependent conservative recombination predominantly occurs between inverted repeats, thereby suppressing formation of isochromosomes whose arms are mirror ima...

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Detalles Bibliográficos
Autores principales: Onaka, Atsushi T., Su, Jie, Katahira, Yasuhiro, Tang, Crystal, Zafar, Faria, Aoki, Keita, Kagawa, Wataru, Niki, Hironori, Iwasaki, Hiroshi, Nakagawa, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193609/
https://www.ncbi.nlm.nih.gov/pubmed/32355220
http://dx.doi.org/10.1038/s42003-020-0934-0

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