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Keratinocyte transglutaminase 2 promotes CCR6(+) γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation

Keratinocyte-derived cytokines and chemokines amplify psoriatic inflammation by recruiting IL-17-producing CCR6(+) γδT-cells and neutrophils. The expression of these cytokines and chemokines mainly depends on NF-κB activity; however, the pathway that activates NF-κB in response to triggering factors...

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Detalles Bibliográficos
Autores principales: Shin, Ji-Woong, Kwon, Mee-ae, Hwang, Jinha, Lee, Seok-Jin, Lee, Jin-Haeng, Kim, Hyo-Jun, Lee, Ki Baek, Lee, Soo-Jin, Jeong, Eui Man, Chung, Jin Ho, Kim, In-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193648/
https://www.ncbi.nlm.nih.gov/pubmed/32355189
http://dx.doi.org/10.1038/s41419-020-2495-z