An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor

A green synthetic protocol has been developed for the efficient preparation of 2,3-dihydroquinazolin−4(1H)-one derivatives with excellent yield in aqueous media. Reverse zinc oxide micelles catalyzed the reactions efficiently and selectively as the hallow nanoreactor. Moreover, the catalyst was reus...

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Autores principales: Mou, Jie, Chen, Ninghai, Zhao, Yu, Qi, Hao, Meng, Sihan, Xiang, Rui, Pei, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193868/
https://www.ncbi.nlm.nih.gov/pubmed/32391312
http://dx.doi.org/10.3389/fchem.2020.00239
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author Mou, Jie
Chen, Ninghai
Zhao, Yu
Qi, Hao
Meng, Sihan
Xiang, Rui
Pei, Dongsheng
author_facet Mou, Jie
Chen, Ninghai
Zhao, Yu
Qi, Hao
Meng, Sihan
Xiang, Rui
Pei, Dongsheng
author_sort Mou, Jie
collection PubMed
description A green synthetic protocol has been developed for the efficient preparation of 2,3-dihydroquinazolin−4(1H)-one derivatives with excellent yield in aqueous media. Reverse zinc oxide micelles catalyzed the reactions efficiently and selectively as the hallow nanoreactor. Moreover, the catalyst was reusable without significant loss of catalytic efficiency. The notable advantages of the procedure are high yields and mild reaction conditions, simple operation, nonchromatographic purification, environmentally friendly and good versatile substrates.
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spelling pubmed-71938682020-05-08 An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor Mou, Jie Chen, Ninghai Zhao, Yu Qi, Hao Meng, Sihan Xiang, Rui Pei, Dongsheng Front Chem Chemistry A green synthetic protocol has been developed for the efficient preparation of 2,3-dihydroquinazolin−4(1H)-one derivatives with excellent yield in aqueous media. Reverse zinc oxide micelles catalyzed the reactions efficiently and selectively as the hallow nanoreactor. Moreover, the catalyst was reusable without significant loss of catalytic efficiency. The notable advantages of the procedure are high yields and mild reaction conditions, simple operation, nonchromatographic purification, environmentally friendly and good versatile substrates. Frontiers Media S.A. 2020-04-24 /pmc/articles/PMC7193868/ /pubmed/32391312 http://dx.doi.org/10.3389/fchem.2020.00239 Text en Copyright © 2020 Mou, Chen, Zhao, Qi, Meng, Xiang and Pei. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Mou, Jie
Chen, Ninghai
Zhao, Yu
Qi, Hao
Meng, Sihan
Xiang, Rui
Pei, Dongsheng
An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor
title An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor
title_full An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor
title_fullStr An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor
title_full_unstemmed An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor
title_short An Aqueous Facile Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives by Reverse Zinc Oxide Micelles as Nanoreactor
title_sort aqueous facile synthesis of 2,3-dihydroquinazolin-4(1h)-one derivatives by reverse zinc oxide micelles as nanoreactor
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193868/
https://www.ncbi.nlm.nih.gov/pubmed/32391312
http://dx.doi.org/10.3389/fchem.2020.00239
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