Oxysterol 25-hydroxycholesterol as a metabolic pathophysiological factors of osteoarthritis induces apoptosis in primary rat chondrocytes

The aim of the present study was to investigate the pathophysiological etiology of osteoarthritis that is mediated by the apoptosis of chondrocytes exposed to 25-hydroxycholesterol (25-HC), an oxysterol synthesized by the expression of cholesterol-25-hydroxylase (CH25H) under inflammatory conditions...

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Detalles Bibliográficos
Autores principales: Seo, Yo-Seob, Cho, In-A, Kim, Tae-Hyeon, You, Jae-Seek, Oh, Ji-Su, Lee, Gyeong-Je, Kim, Do Kyung, Kim, Jae-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193916/
https://www.ncbi.nlm.nih.gov/pubmed/32392916
http://dx.doi.org/10.4196/kjpp.2020.24.3.249

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