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Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole
BACKGROUND AND PURPOSE: Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adv...
Autores principales: | Udawatte, Nadeeka S., Kang, Sung Wook, Wang, Yue, Arumugam, Thiruma V., Seneviratne, Chaminda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193989/ https://www.ncbi.nlm.nih.gov/pubmed/32390849 http://dx.doi.org/10.3389/fphar.2020.00511 |
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