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Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole

BACKGROUND AND PURPOSE: Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adv...

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Detalles Bibliográficos
Autores principales: Udawatte, Nadeeka S., Kang, Sung Wook, Wang, Yue, Arumugam, Thiruma V., Seneviratne, Chaminda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193989/
https://www.ncbi.nlm.nih.gov/pubmed/32390849
http://dx.doi.org/10.3389/fphar.2020.00511

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