hERG K(+) Channels Promote Survival of Irradiated Leukemia Cells

Many tumor cells express highly elevated activities of voltage-gated K(+) channels in the plasma membrane which are indispensable for tumor growth. To test for K(+) channel function during DNA damage response, we subjected human chronic myeloid leukemia (CML) cells to sub-lethal doses of ionizing ra...

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Detalles Bibliográficos
Autores principales: Palme, Daniela, Misovic, Milan, Ganser, Katrin, Klumpp, Lukas, Salih, Helmut R., Zips, Daniel, Huber, Stephan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194033/
https://www.ncbi.nlm.nih.gov/pubmed/32390841
http://dx.doi.org/10.3389/fphar.2020.00489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194033/
https://www.ncbi.nlm.nih.gov/pubmed/32390841
http://dx.doi.org/10.3389/fphar.2020.00489

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