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Light as a potential treatment for pandemic coronavirus infections: A perspective

The recent outbreak of COVID-19, which continues to ravage communities with high death tolls and untold psychosocial and catastrophic economic consequences, is a vivid reminder of nature's capacity to defy contemporary healthcare. The pandemic calls for rapid mobilization of every potential cli...

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Autores principales: Enwemeka, Chukuka Samuel, Bumah, Violet Vakunseh, Masson-Meyers, Daniela Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194064/
https://www.ncbi.nlm.nih.gov/pubmed/32388486
http://dx.doi.org/10.1016/j.jphotobiol.2020.111891
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author Enwemeka, Chukuka Samuel
Bumah, Violet Vakunseh
Masson-Meyers, Daniela Santos
author_facet Enwemeka, Chukuka Samuel
Bumah, Violet Vakunseh
Masson-Meyers, Daniela Santos
author_sort Enwemeka, Chukuka Samuel
collection PubMed
description The recent outbreak of COVID-19, which continues to ravage communities with high death tolls and untold psychosocial and catastrophic economic consequences, is a vivid reminder of nature's capacity to defy contemporary healthcare. The pandemic calls for rapid mobilization of every potential clinical tool, including phototherapy—one of the most effective treatments used to reduce the impact of the 1918 “Spanish influenza” pandemic. This paper cites several studies showing that phototherapy has immense potential to reduce the impact of coronavirus diseases, and offers suggested ways that the healthcare industry can integrate modern light technologies in the fight against COVID-19 and other infections. The evidence shows that violet/blue (400–470 nm) light is antimicrobial against numerous bacteria, and that it accounts for Niels Ryberg Finsen's Nobel-winning treatment of tuberculosis. Further evidence shows that blue light inactivates several viruses, including the common flu coronavirus, and that in experimental animals, red and near infrared light reduce respiratory disorders, similar to those complications associated with coronavirus infection. Moreover, in patients, red light has been shown to alleviate chronic obstructive lung disease and bronchial asthma. These findings call for urgent efforts to further explore the clinical value of light, and not wait for another pandemic to serve as a reminder. The ubiquity of inexpensive light emitting lasers and light emitting diodes (LEDs), makes it relatively easy to develop safe low-cost light-based devices with the potential to reduce infections, sanitize equipment, hospital facilities, emergency care vehicles, homes, and the general environment as pilot studies have shown.
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spelling pubmed-71940642020-05-02 Light as a potential treatment for pandemic coronavirus infections: A perspective Enwemeka, Chukuka Samuel Bumah, Violet Vakunseh Masson-Meyers, Daniela Santos J Photochem Photobiol B Article The recent outbreak of COVID-19, which continues to ravage communities with high death tolls and untold psychosocial and catastrophic economic consequences, is a vivid reminder of nature's capacity to defy contemporary healthcare. The pandemic calls for rapid mobilization of every potential clinical tool, including phototherapy—one of the most effective treatments used to reduce the impact of the 1918 “Spanish influenza” pandemic. This paper cites several studies showing that phototherapy has immense potential to reduce the impact of coronavirus diseases, and offers suggested ways that the healthcare industry can integrate modern light technologies in the fight against COVID-19 and other infections. The evidence shows that violet/blue (400–470 nm) light is antimicrobial against numerous bacteria, and that it accounts for Niels Ryberg Finsen's Nobel-winning treatment of tuberculosis. Further evidence shows that blue light inactivates several viruses, including the common flu coronavirus, and that in experimental animals, red and near infrared light reduce respiratory disorders, similar to those complications associated with coronavirus infection. Moreover, in patients, red light has been shown to alleviate chronic obstructive lung disease and bronchial asthma. These findings call for urgent efforts to further explore the clinical value of light, and not wait for another pandemic to serve as a reminder. The ubiquity of inexpensive light emitting lasers and light emitting diodes (LEDs), makes it relatively easy to develop safe low-cost light-based devices with the potential to reduce infections, sanitize equipment, hospital facilities, emergency care vehicles, homes, and the general environment as pilot studies have shown. The Authors. Published by Elsevier B.V. 2020-06 2020-05-01 /pmc/articles/PMC7194064/ /pubmed/32388486 http://dx.doi.org/10.1016/j.jphotobiol.2020.111891 Text en © 2021 The Authors. Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Enwemeka, Chukuka Samuel
Bumah, Violet Vakunseh
Masson-Meyers, Daniela Santos
Light as a potential treatment for pandemic coronavirus infections: A perspective
title Light as a potential treatment for pandemic coronavirus infections: A perspective
title_full Light as a potential treatment for pandemic coronavirus infections: A perspective
title_fullStr Light as a potential treatment for pandemic coronavirus infections: A perspective
title_full_unstemmed Light as a potential treatment for pandemic coronavirus infections: A perspective
title_short Light as a potential treatment for pandemic coronavirus infections: A perspective
title_sort light as a potential treatment for pandemic coronavirus infections: a perspective
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194064/
https://www.ncbi.nlm.nih.gov/pubmed/32388486
http://dx.doi.org/10.1016/j.jphotobiol.2020.111891
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