Cargando…

Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses

Mast cells are tissue-resident innate immune cells known for their prominent role in mediating allergic reactions. MAS-related G-protein coupled receptor-X2 (MRGPRX2) is a promiscuous G-protein coupled receptor (GPCR) expressed on mast cells that is activated by several ligands that share cationic a...

Descripción completa

Detalles Bibliográficos
Autores principales: Callahan, Brianna N., Kammala, Ananth K., Syed, Meesum, Yang, Canchai, Occhiuto, Christopher J., Nellutla, Rithvik, Chumanevich, Alena P., Oskeritzian, Carole A., Das, Rupali, Subramanian, Hariharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194083/
https://www.ncbi.nlm.nih.gov/pubmed/32391014
http://dx.doi.org/10.3389/fimmu.2020.00703

Ejemplares similares