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Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses
Mast cells are tissue-resident innate immune cells known for their prominent role in mediating allergic reactions. MAS-related G-protein coupled receptor-X2 (MRGPRX2) is a promiscuous G-protein coupled receptor (GPCR) expressed on mast cells that is activated by several ligands that share cationic a...
Autores principales: | Callahan, Brianna N., Kammala, Ananth K., Syed, Meesum, Yang, Canchai, Occhiuto, Christopher J., Nellutla, Rithvik, Chumanevich, Alena P., Oskeritzian, Carole A., Das, Rupali, Subramanian, Hariharan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194083/ https://www.ncbi.nlm.nih.gov/pubmed/32391014 http://dx.doi.org/10.3389/fimmu.2020.00703 |
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