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Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies

The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more responsive than are binucleated cardiomyocytes to proprolife...

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Detalles Bibliográficos
Autores principales: Windmueller, Rebecca, Leach, John P., Babu, Apoorva, Zhou, Su, Morley, Michael P., Wakabayashi, Aoi, Petrenko, Nataliya B., Viatour, Patrick, Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194103/
https://www.ncbi.nlm.nih.gov/pubmed/32130910
http://dx.doi.org/10.1016/j.celrep.2020.02.034

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