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Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies
The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more responsive than are binucleated cardiomyocytes to proprolife...
Autores principales: | Windmueller, Rebecca, Leach, John P., Babu, Apoorva, Zhou, Su, Morley, Michael P., Wakabayashi, Aoi, Petrenko, Nataliya B., Viatour, Patrick, Morrisey, Edward E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194103/ https://www.ncbi.nlm.nih.gov/pubmed/32130910 http://dx.doi.org/10.1016/j.celrep.2020.02.034 |
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