Necrostatin-1 Ameliorates Neutrophilic Inflammation in Asthma by Suppressing MLKL Phosphorylation to Inhibiting NETs Release

Neutrophilic inflammation occurs during asthma exacerbation, and especially, in patients with steroid-refractory asthma, but the underlying mechanisms are poorly understood. Recently, a significant accumulation of neutrophil extracellular traps (NETs) in the airways of neutrophilic asthma has been d...

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Detalles Bibliográficos
Autores principales: Han, X. A., Jie, H. Y., Wang, J. H., Zhang, X. M., Wang, Jun, Yu, C. X., Zhang, J. L., He, J., Chen, J. Q., Lai, K. F., Sun, E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194114/
https://www.ncbi.nlm.nih.gov/pubmed/32391007
http://dx.doi.org/10.3389/fimmu.2020.00666

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