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The Impact of Plasma Protein Binding Characteristics and Unbound Concentration of Voriconazole on Its Adverse Drug Reactions

This study investigated voriconazole (VRC) unbound plasma concentration and its relationship with adverse drug reactions (ADRs) in patients with malignant hematologic disease. Plasma samples were collected from patients or spiked in vitro. A time-saving rapid equilibrium dialysis assay was used for...

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Detalles Bibliográficos
Autores principales:	Yuan, Zi-Qing-Yun, Qiao, Chun, Yang, Zhi-Cheng, Yu, Lei, Sun, Lu-Ning, Qian, Yi, Zhang, Xue-Hui, Meng, Ling, Zhang, Xiao-Yan, Wang, Yong-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194128/ https://www.ncbi.nlm.nih.gov/pubmed/32390847 http://dx.doi.org/10.3389/fphar.2020.00505

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