Cargando…

Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells

Goshajinkigan (GJG) is a traditional Japanese Kampo medicine used clinically to treat muscle pain in Japan. However, its underlying mechanism remains unclear. Since voltage-gated sodium channel (Nav) 1.4 is involved in skeletal muscle contraction, we investigated the possibility that GJG may affect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Imai, Ryota, Horita, Shoichiro, Ono, Yuko, Hagihara, Keisuke, Shimizu, Masaru, Maejima, Yuko, Shimomura, Kenju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2020
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194311/ https://www.ncbi.nlm.nih.gov/pubmed/32368413 http://dx.doi.org/10.1089/biores.2019.0034

Ejemplares similares

The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats
por: Maejima, Yuko, et al.
Publicado: (2019)

Early life high-fat diet exposure evokes normal weight obesity
por: Maejima, Yuko, et al.
Publicado: (2020)

The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity
por: Maejima, Yuko, et al.
Publicado: (2021)

Memantine has no effect on K(ATP) channels in pancreatic β cells
por: Imai, Ryota, et al.
Publicado: (2018)

Soluble interleukin-2 receptor as a predictive and prognostic marker for patients with familial breast cancer
por: Gonda, Kenji, et al.
Publicado: (2021)

TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice
por: Ono, Yuko, et al.
Publicado: (2020)

Identification of oxytocin receptor activating chemical components from traditional Japanese medicines
por: Maejima, Yuko, et al.
Publicado: (2021)

Structure based analysis of K(ATP) channel with a DEND syndrome mutation in murine skeletal muscle
por: Horita, Shoichiro, et al.
Publicado: (2021)

Association between cognitive impairment patient with solid cancer and insulin resistance
por: Gonda, Kenji, et al.
Publicado: (2019)

Efficacy of SGLT2 inhibitors as additional treatment in Japanese type 2 diabetic patients: second or third choice?
por: Fujiwara, Makoto, et al.
Publicado: (2022)

The hypothalamus to brainstem circuit suppresses late-onset body weight gain
por: Maejima, Yuko, et al.
Publicado: (2019)

The effects of ninjin’yoeito on the electrophysiological properties of dopamine neurons in the ventral tegmental area/substantia nigra pars compacta and medium spiny neurons in the nucleus accumbens
por: Imai, Ryota, et al.
Publicado: (2022)

K(ATP) Channel Mutations and Neonatal Diabetes
por: Shimomura, Kenju, et al.
Publicado: (2017)

C188-9, a specific inhibitor of STAT3 signaling, prevents thermal burn-induced skeletal muscle wasting in mice
por: Ono, Yuko, et al.
Publicado: (2022)

Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion
por: Kitamura, Shigeki, et al.
Publicado: (2023)

Detection of NUCB2/nesfatin-1 in cerebrospinal fluid of multiple sclerosis patients
por: Shimizu, Masaru, et al.
Publicado: (2020)

Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3
por: Ghovanloo, Mohammad-Reza, et al.
Publicado: (2018)

Dose Dependent Effect of Sulfamethoxazole on Inhibiting K(ATP) Channel of Mouse Pancreatic β Cell
por: Ogata, Hiroshi, et al.
Publicado: (2023)

The effectiveness of traditional Japanese medicine Goshajinkigan in irradiation-induced aspermatogenesis in mice
por: Takahashi, Kumpei, et al.
Publicado: (2019)

Na(+)/Ca(2+) selectivity in the bacterial voltage-gated sodium channel NavAb
por: Corry, Ben
Publicado: (2013)

The effect of avertin anesthesia and a mixture of three types of anesthetic agents on food intakeand body weight in high fat-induced obese maleand female mice
por: Maejima, Yuko, et al.
Publicado: (2018)

Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity
por: Kerth, Clara M., et al.
Publicado: (2020)

Voltage sensor dynamics of a bacterial voltage-gated sodium channel NavAb reveal three conformational states
por: Han, Shuo, et al.
Publicado: (2023)

Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics
por: Dvorak, Nolan M., et al.
Publicado: (2020)

The Functional Role of Voltage-Gated Sodium Channel Nav1.5 in Metastatic Breast Cancer
por: Luo, Qianxuan, et al.
Publicado: (2020)

Role of the voltage-gated sodium channel Nav1.6 in glioma and candidate drugs screening
por: Ai, Yong, et al.
Publicado: (2023)

Goshajinkigan attenuates paclitaxel‐induced neuropathic pain via cortical astrocytes
por: Takanashi, Kenta, et al.
Publicado: (2021)

Evaluation of organ glucose metabolism by (18)F-FDG accumulation with insulin loading in aged mice compared with young normal mice
por: Zhao, Jingmin, et al.
Publicado: (2021)

Evaluation of Effect of Ninjin'yoeito on Regional Brain Glucose Metabolism by (18)F-FDG Autoradiography With Insulin Loading in Aged Mice
por: Zhao, Jingmin, et al.
Publicado: (2021)

MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 years
por: Momma, Tomoyuki, et al.
Publicado: (2019)

Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women
por: Tokita, Yoshiharu, et al.
Publicado: (2017)

The Sigma-1 Receptor Binds to the Nav1.5 Voltage-gated Na(+) Channel with 4-Fold Symmetry
por: Balasuriya, Dilshan, et al.
Publicado: (2012)

Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report
por: Gonda, Kenji, et al.
Publicado: (2019)

The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action
por: Matsumura, Yukiko, et al.
Publicado: (2014)

Drug-interaction between paclitaxel and goshajinkigan extract and its constituents
por: Nakayama, Akiko, et al.
Publicado: (2021)

Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy
por: Kono, Toru, et al.
Publicado: (2013)

Impact of sex, fat distribution and initial body weight on oxytocin’s body weight regulation
por: Maejima, Yuko, et al.
Publicado: (2017)

Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ(1−42)
por: Wang, Xi, et al.
Publicado: (2016)

Thermal melt circular dichroism spectroscopic studies for identifying stabilising amphipathic molecules for the voltage‐gated sodium channel NavMs
por: Ireland, Sam M., et al.
Publicado: (2017)

MiR-30b Attenuates Neuropathic Pain by Regulating Voltage-Gated Sodium Channel Nav1.3 in Rats
por: Su, Songxue, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4ljm1682rlbs17f428kk8otivv