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Validation of a commercial antibody to detect endogenous human nicastrin by immunoblot

Nicastrin (NCSTN) is a transmembrane glycoprotein that is part of the gamma-secretase complex. Gamma-secretase is a protease complex that cleaves type-I single-pass transmembrane proteins. There are many potential substrates for this complex, including NOTCH receptors and amyloid precursor proteins...

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Detalles Bibliográficos
Autores principales:	Mesa, Rosana A., Roberson, Elisha D.O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2020
Materias:	Antibody Validation Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194342/ https://www.ncbi.nlm.nih.gov/pubmed/32399180 http://dx.doi.org/10.12688/f1000research.19803.2

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