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TGF-beta and TNF-alpha cooperatively induce mesenchymal transition of lymphatic endothelial cells via activation of Activin signals

Lymphatic systems play important roles in the maintenance of fluid homeostasis and undergo anatomical and physiological changes during inflammation and aging. While lymphatic endothelial cells (LECs) undergo mesenchymal transition in response to transforming growth factor-β (TGF-β), the molecular me...

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Detalles Bibliográficos
Autores principales: Yoshimatsu, Yasuhiro, Kimuro, Shiori, Pauty, Joris, Takagaki, Kazuki, Nomiyama, Sanae, Inagawa, Akihiko, Maeda, Kentaro, Podyma-Inoue, Katarzyna A., Kajiya, Kentaro, Matsunaga, Yukiko T., Watabe, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194440/
https://www.ncbi.nlm.nih.gov/pubmed/32357159
http://dx.doi.org/10.1371/journal.pone.0232356