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Diabète et COVID-19

According to previous reports, diabetes seems to be associated with serious clinical events due to COVID-19. But is diabetes per se a risk factor of being infected by the virus? We discuss these points. Data about the antidiabetic drugs are scarce. Dipeptidylpeptidase-4 (DPP-4) is found as both a ce...

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Autores principales: Bouhanick, Béatrice, Cracowski, Jean-Luc, Faillie, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS on behalf of Société française de pharmacologie et de thérapeutique. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194540/
https://www.ncbi.nlm.nih.gov/pubmed/33965234
http://dx.doi.org/10.1016/j.therap.2020.04.004
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author Bouhanick, Béatrice
Cracowski, Jean-Luc
Faillie, Jean-Luc
author_facet Bouhanick, Béatrice
Cracowski, Jean-Luc
Faillie, Jean-Luc
author_sort Bouhanick, Béatrice
collection PubMed
description According to previous reports, diabetes seems to be associated with serious clinical events due to COVID-19. But is diabetes per se a risk factor of being infected by the virus? We discuss these points. Data about the antidiabetic drugs are scarce. Dipeptidylpeptidase-4 (DPP-4) is found as both a cell surface protein ubiquitously expressed in many tissues and as a soluble molecule found in serum/plasma, fluids. DPP-4 is involved in infection of cells by some viruses. We relate data about the use of DPP-4 inhibitors in diabetic patients. We conclude relating French and international recommendations in people with diabetes.
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spelling pubmed-71945402020-05-02 Diabète et COVID-19 Bouhanick, Béatrice Cracowski, Jean-Luc Faillie, Jean-Luc Therapie Article Original According to previous reports, diabetes seems to be associated with serious clinical events due to COVID-19. But is diabetes per se a risk factor of being infected by the virus? We discuss these points. Data about the antidiabetic drugs are scarce. Dipeptidylpeptidase-4 (DPP-4) is found as both a cell surface protein ubiquitously expressed in many tissues and as a soluble molecule found in serum/plasma, fluids. DPP-4 is involved in infection of cells by some viruses. We relate data about the use of DPP-4 inhibitors in diabetic patients. We conclude relating French and international recommendations in people with diabetes. Published by Elsevier Masson SAS on behalf of Société française de pharmacologie et de thérapeutique. 2020-04-23 /pmc/articles/PMC7194540/ /pubmed/33965234 http://dx.doi.org/10.1016/j.therap.2020.04.004 Text en © 2020 Published by Elsevier Masson SAS on behalf of Société française de pharmacologie et de thérapeutique. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article Original
Bouhanick, Béatrice
Cracowski, Jean-Luc
Faillie, Jean-Luc
Diabète et COVID-19
title Diabète et COVID-19
title_full Diabète et COVID-19
title_fullStr Diabète et COVID-19
title_full_unstemmed Diabète et COVID-19
title_short Diabète et COVID-19
title_sort diabète et covid-19
topic Article Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194540/
https://www.ncbi.nlm.nih.gov/pubmed/33965234
http://dx.doi.org/10.1016/j.therap.2020.04.004
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