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Two cases of coronavirus 2019–related cardiomyopathy in pregnancy

At our institution, 2 of the initial 7 pregnant patients with confirmed coronavirus disease 2019 severe infection (28.6%; 95% CI, 8.2%–64.1%) developed cardiac dysfunction with moderately reduced left ventricular ejection fractions of 40%–45% and hypokinesis. Viral myocarditis and cardiomyopathy hav...

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Detalles Bibliográficos
Autores principales: Juusela, Alexander, Nazir, Munir, Gimovsky, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194868/
https://www.ncbi.nlm.nih.gov/pubmed/32363336
http://dx.doi.org/10.1016/j.ajogmf.2020.100113
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author Juusela, Alexander
Nazir, Munir
Gimovsky, Martin
author_facet Juusela, Alexander
Nazir, Munir
Gimovsky, Martin
author_sort Juusela, Alexander
collection PubMed
description At our institution, 2 of the initial 7 pregnant patients with confirmed coronavirus disease 2019 severe infection (28.6%; 95% CI, 8.2%–64.1%) developed cardiac dysfunction with moderately reduced left ventricular ejection fractions of 40%–45% and hypokinesis. Viral myocarditis and cardiomyopathy have also been reported in nonpregnant coronavirus disease 2019 patients. A case series of nonpregnant patients with coronavirus disease 2019 found that 33% of those in intensive care developed cardiomyopathy. More data are needed to ascertain the incidence of cardiomyopathy from coronavirus disease 2019 in pregnancy, in all pregnant women with coronavirus disease 2019, and those with severe disease (eg, pneumonia). We suggest an echocardiogram in pregnant women with coronavirus disease 2019 pneumonia, in particular those necessitating oxygen, or those who are critically ill, and we recommend the use of handheld, point-of-care devices where possible to minimize contamination of staff and traditional large echocardiogram machines.
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spelling pubmed-71948682020-05-02 Two cases of coronavirus 2019–related cardiomyopathy in pregnancy Juusela, Alexander Nazir, Munir Gimovsky, Martin Am J Obstet Gynecol MFM Case Series At our institution, 2 of the initial 7 pregnant patients with confirmed coronavirus disease 2019 severe infection (28.6%; 95% CI, 8.2%–64.1%) developed cardiac dysfunction with moderately reduced left ventricular ejection fractions of 40%–45% and hypokinesis. Viral myocarditis and cardiomyopathy have also been reported in nonpregnant coronavirus disease 2019 patients. A case series of nonpregnant patients with coronavirus disease 2019 found that 33% of those in intensive care developed cardiomyopathy. More data are needed to ascertain the incidence of cardiomyopathy from coronavirus disease 2019 in pregnancy, in all pregnant women with coronavirus disease 2019, and those with severe disease (eg, pneumonia). We suggest an echocardiogram in pregnant women with coronavirus disease 2019 pneumonia, in particular those necessitating oxygen, or those who are critically ill, and we recommend the use of handheld, point-of-care devices where possible to minimize contamination of staff and traditional large echocardiogram machines. Elsevier Inc. 2020-05 2020-04-03 /pmc/articles/PMC7194868/ /pubmed/32363336 http://dx.doi.org/10.1016/j.ajogmf.2020.100113 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Series
Juusela, Alexander
Nazir, Munir
Gimovsky, Martin
Two cases of coronavirus 2019–related cardiomyopathy in pregnancy
title Two cases of coronavirus 2019–related cardiomyopathy in pregnancy
title_full Two cases of coronavirus 2019–related cardiomyopathy in pregnancy
title_fullStr Two cases of coronavirus 2019–related cardiomyopathy in pregnancy
title_full_unstemmed Two cases of coronavirus 2019–related cardiomyopathy in pregnancy
title_short Two cases of coronavirus 2019–related cardiomyopathy in pregnancy
title_sort two cases of coronavirus 2019–related cardiomyopathy in pregnancy
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194868/
https://www.ncbi.nlm.nih.gov/pubmed/32363336
http://dx.doi.org/10.1016/j.ajogmf.2020.100113
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