Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Host genetic factors play a fundamental role in regulating humoral immunity to viral infection, including influenza A virus (IAV). Here, we utilize the Collaborative Cross (CC), a mouse genetic reference population, to study genetic regulation of variation in antibody response following IAV infectio...

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Detalles Bibliográficos
Autores principales: Noll, Kelsey E., Whitmore, Alan C., West, Ande, McCarthy, Mary K., Morrison, Clayton R., Plante, Kenneth S., Hampton, Brea K., Kollmus, Heike, Pilzner, Carolin, Leist, Sarah R., Gralinski, Lisa E., Menachery, Vineet D., Schäfer, Alexandra, Miller, Darla, Shaw, Ginger, Mooney, Michael, McWeeney, Shannon, Pardo-Manuel de Villena, Fernando, Schughart, Klaus, Morrison, Thomas E., Baric, Ralph S., Ferris, Martin T., Heise, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195006/
https://www.ncbi.nlm.nih.gov/pubmed/32348764
http://dx.doi.org/10.1016/j.celrep.2020.107587

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