Cargando…

Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy

BACKGROUND: SARS-CoV-2 is a new coronavirus that has spread globally, infecting more than 150000 people, and being declared pandemic by the WHO. We provide here bio-informatic, evolutionary analysis of 351 available sequences of its genome with the aim of mapping genome structural variations and the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Benvenuto, Domenico, Angeletti, Silvia, Giovanetti, Marta, Bianchi, Martina, Pascarella, Stefano, Cauda, Roberto, Ciccozzi, Massimo, Cassone, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Infection Association. Published by Elsevier Ltd. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195303/ https://www.ncbi.nlm.nih.gov/pubmed/32283146 http://dx.doi.org/10.1016/j.jinf.2020.03.058

Ejemplares similares

Shortening Epitopes to Survive: The Case of SARS-CoV-2 Lambda Variant
por: Pascarella, Stefano, et al.
Publicado: (2021)

The Biological Properties of the SARS-CoV-2 Cameroon Variant Spike: An Intermediate between the Alpha and Delta Variants
por: Pascarella, Stefano, et al.
Publicado: (2022)

The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
por: Pascarella, Stefano, et al.
Publicado: (2022)

Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?
por: Bianchi, Martina, et al.
Publicado: (2020)

SARS‐CoV‐2 B.1.617 Indian variants: Are electrostatic potential changes responsible for a higher transmission rate?
por: Pascarella, Stefano, et al.
Publicado: (2021)

Peculiar Variations of the Electrostatic Potential of Spike Protein N-terminal Domain Associated with the Emergence of Successive SARS-CoV-2 Omicron Lineages
por: Pascarella, Stefano, et al.
Publicado: (2023)

Emerging of a SARS-CoV-2 viral strain with a deletion in nsp1
por: Benedetti, Francesca, et al.
Publicado: (2020)

Application of the ARIMA model on the COVID-2019 epidemic dataset
por: Benvenuto, Domenico, et al.
Publicado: (2020)

The global spread of 2019-nCoV: a molecular evolutionary analysis
por: Benvenuto, Domenico, et al.
Publicado: (2020)

Genetic and Structural Data on the SARS-CoV-2 Omicron BQ.1 Variant Reveal Its Low Potential for Epidemiological Expansion
por: Scarpa, Fabio, et al.
Publicado: (2022)

Molecular In-Depth on the Epidemiological Expansion of SARS-CoV-2 XBB.1.5
por: Scarpa, Fabio, et al.
Publicado: (2023)

Genetic and structural genome-based survey reveals the low potential for epidemiological expansion of the SARS-CoV-2 XBB.1.5 sublineage
por: Scarpa, Fabio, et al.
Publicado: (2023)

Coronavirus NSP6 protein (nsp6)
Publicado: (2014)

SARS-Cov-2 ORF3a: Mutability and function
por: Bianchi, Martina, et al.
Publicado: (2021)

Identification of the nucleotide substitutions in 62 SARS-CoV-2 sequences from Turkey
por: DEMİR, Ayşe Banu, et al.
Publicado: (2020)

Hepatitis E Virus Circulation in Italy: Phylogenetic and Evolutionary Analysis
por: Montesano, Carla, et al.
Publicado: (2016)

Khosta: A Genetic and Structural Point of View of the Forgotten Virus
por: Scarpa, Fabio, et al.
Publicado: (2023)

Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
por: Ciccozzi, Massimo, et al.
Publicado: (2023)

Involvement of PRRSV NSP3 and NSP5 in the autophagy process
por: Zhang, Wei, et al.
Publicado: (2019)

Coronavirus NSP6 restricts autophagosome expansion
por: Cottam, Eleanor M, et al.
Publicado: (2014)

SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists
por: Yuen, Chun-Kit, et al.
Publicado: (2020)

Implications of Possible HBV-Driven Regulation of Gene Expression in Stem Cell-like Subpopulation of Huh-7 Hepatocellular Carcinoma Cell Line
por: Demir, Ayse Banu, et al.
Publicado: (2022)

Assessment of core and support functions of the communicable disease surveillance system in the Kurdistan Region of Iraq
por: Hamalaw, Soran Amin, et al.
Publicado: (2021)

Human Immunodeficiency Virus Type 2: The Neglected Threat
por: Ceccarelli, Giancarlo, et al.
Publicado: (2021)

SARS-CoV-2 Recombinants: Genomic Comparison between XBF and Its Parental Lineages
por: Scarpa, Fabio, et al.
Publicado: (2023)

Update on the Phylodynamic and Genetic Variability of Marburg Virus
por: Scarpa, Fabio, et al.
Publicado: (2023)

Integrative Genome-Based Survey of the SARS-CoV-2 Omicron XBB.1.16 Variant
por: Scarpa, Fabio, et al.
Publicado: (2023)

SARS-CoV CH.1.1 Variant: Genomic and Structural Insight
por: Bazzani, Liliana, et al.
Publicado: (2023)

Effects of chloroquine on viral infections: an old drug against today's diseases
por: Savarino, Adrea, et al.
Publicado: (2003)

COVID‐19 sniffer dog experimental training: Which protocol and which implications for reliable sidentification?
por: Angeletti, Silvia, et al.
Publicado: (2021)

Update on the Phylodynamics of SADS-CoV
por: Scarpa, Fabio, et al.
Publicado: (2021)

The variants question: What is the problem?
por: Zella, Davide, et al.
Publicado: (2021)

Evolution patterns of SARS-CoV-2: Snapshot on its genome variants
por: Giovanetti, Marta, et al.
Publicado: (2021)

SARS-CoV-2 viral genes Nsp6, Nsp8, and M compromise cellular ATP levels to impair survival and function of human pluripotent stem cell-derived cardiomyocytes
por: Liu, Juli, et al.
Publicado: (2023)

Could NSP5a3a be a target for head and neck cancer?
por: White, Martyn K., et al.
Publicado: (2010)

Whole Genome Analysis of African G12P[6] and G12P[8] Rotaviruses Provides Evidence of Porcine-Human Reassortment at NSP2, NSP3, and NSP4
por: Mokoena, Fortunate, et al.
Publicado: (2021)

Screening of FDA-approved compound library identifies potential small-molecule inhibitors of SARS-CoV-2 non-structural proteins NSP1, NSP4, NSP6 and NSP13: molecular modeling and molecular dynamics studies
por: Sundar, Shobana, et al.
Publicado: (2021)

The multiple roles of nsp6 in the molecular pathogenesis of SARS-CoV-2
por: Bills, Cody, et al.
Publicado: (2023)

SARS-CoV-2 shifting transmission dynamics and hidden reservoirs potentially limit efficacy of public health interventions in Italy
por: Giovanetti, Marta, et al.
Publicado: (2021)

Multicomponent vaccines to fight SARS-CoV-2 variants of concern
por: Cassone, Antonio, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3e7c4q2ob31rs3tbkbccr5h7g1