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Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection

As of March 24, 2020, novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for 379,661 infection cases with 16,428 deaths globally, and the number is still increasing rapidly. Herein, we present four critically ill patients with SARS-CoV-2 infection who received su...

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Autores principales: Zhang, Bin, Liu, Shuyi, Tan, Tan, Huang, Wenhui, Dong, Yuhao, Chen, Luyan, Chen, Qiuying, Zhang, Lu, Zhong, Qingyang, Zhang, Xiaoping, Zou, Yujian, Zhang, Shuixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc under license from the American College of Chest Physicians. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195335/
https://www.ncbi.nlm.nih.gov/pubmed/32243945
http://dx.doi.org/10.1016/j.chest.2020.03.039
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author Zhang, Bin
Liu, Shuyi
Tan, Tan
Huang, Wenhui
Dong, Yuhao
Chen, Luyan
Chen, Qiuying
Zhang, Lu
Zhong, Qingyang
Zhang, Xiaoping
Zou, Yujian
Zhang, Shuixing
author_facet Zhang, Bin
Liu, Shuyi
Tan, Tan
Huang, Wenhui
Dong, Yuhao
Chen, Luyan
Chen, Qiuying
Zhang, Lu
Zhong, Qingyang
Zhang, Xiaoping
Zou, Yujian
Zhang, Shuixing
author_sort Zhang, Bin
collection PubMed
description As of March 24, 2020, novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for 379,661 infection cases with 16,428 deaths globally, and the number is still increasing rapidly. Herein, we present four critically ill patients with SARS-CoV-2 infection who received supportive care and convalescent plasma. Although all four patients (including a pregnant woman) recovered from SARS-CoV-2 infection eventually, randomized trials are needed to eliminate the effect of other treatments and investigate the safety and efficacy of convalescent plasma therapy.
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spelling pubmed-71953352020-05-02 Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection Zhang, Bin Liu, Shuyi Tan, Tan Huang, Wenhui Dong, Yuhao Chen, Luyan Chen, Qiuying Zhang, Lu Zhong, Qingyang Zhang, Xiaoping Zou, Yujian Zhang, Shuixing Chest Article As of March 24, 2020, novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for 379,661 infection cases with 16,428 deaths globally, and the number is still increasing rapidly. Herein, we present four critically ill patients with SARS-CoV-2 infection who received supportive care and convalescent plasma. Although all four patients (including a pregnant woman) recovered from SARS-CoV-2 infection eventually, randomized trials are needed to eliminate the effect of other treatments and investigate the safety and efficacy of convalescent plasma therapy. The Authors. Published by Elsevier Inc under license from the American College of Chest Physicians. 2020-07 2020-03-31 /pmc/articles/PMC7195335/ /pubmed/32243945 http://dx.doi.org/10.1016/j.chest.2020.03.039 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Zhang, Bin
Liu, Shuyi
Tan, Tan
Huang, Wenhui
Dong, Yuhao
Chen, Luyan
Chen, Qiuying
Zhang, Lu
Zhong, Qingyang
Zhang, Xiaoping
Zou, Yujian
Zhang, Shuixing
Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
title Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
title_full Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
title_fullStr Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
title_full_unstemmed Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
title_short Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
title_sort treatment with convalescent plasma for critically ill patients with severe acute respiratory syndrome coronavirus 2 infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195335/
https://www.ncbi.nlm.nih.gov/pubmed/32243945
http://dx.doi.org/10.1016/j.chest.2020.03.039
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