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Midkine activation of CD8(+) T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
Brain tumors (gliomas) are heterogeneous cellular ecosystems, where non-neoplastic monocytic cells have emerged as key regulators of tumor maintenance and progression. However, relative to macrophages/microglia, comparatively less is known about the roles of neurons and T cells in glioma pathobiolog...
Autores principales: | Guo, Xiaofan, Pan, Yuan, Xiong, Min, Sanapala, Shilpa, Anastasaki, Corina, Cobb, Olivia, Dahiya, Sonika, Gutmann, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195398/ https://www.ncbi.nlm.nih.gov/pubmed/32358581 http://dx.doi.org/10.1038/s41467-020-15770-3 |
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