Photoactivatable Cre recombinase 3.0 for in vivo mouse applications

Optogenetic genome engineering tools enable spatiotemporal control of gene expression and provide new insight into biological function. Here, we report the new version of genetically encoded photoactivatable (PA) Cre recombinase, PA-Cre 3.0. To improve PA-Cre technology, we compare light-dimerizatio...

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Detalles Bibliográficos
Autores principales: Morikawa, Kumi, Furuhashi, Kazuhiro, de Sena-Tomas, Carmen, Garcia-Garcia, Alvaro L., Bekdash, Ramsey, Klein, Alison D., Gallerani, Nicholas, Yamamoto, Hannah E., Park, Seon-Hye E., Collins, Grant S., Kawano, Fuun, Sato, Moritoshi, Lin, Chyuan-Sheng, Targoff, Kimara L., Au, Edmund, Salling, Michael C., Yazawa, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195411/
https://www.ncbi.nlm.nih.gov/pubmed/32358538
http://dx.doi.org/10.1038/s41467-020-16030-0

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