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Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy

Poly-ADP-ribosylation (PARylation) is a fully reversible post-translational modification with key roles in cellular physiology. Due to the multi-domain structure of poly(ADP-ribose) polymerase-1 (PARP1) and the highly dynamic nature of the PARylation reaction, studies on the biochemical mechanism an...

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Detalles Bibliográficos
Autores principales:	Krüger, Annika, Bürkle, Alexander, Hauser, Karin, Mangerich, Aswin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195430/ https://www.ncbi.nlm.nih.gov/pubmed/32358582 http://dx.doi.org/10.1038/s41467-020-15858-w

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