A novel neurodegenerative spectrum disorder in patients with MLKL deficiency

Mixed lineage kinase domain-like (MLKL) is the main executor of necroptosis, an inflammatory form of programmed cell death. Necroptosis is implicated in combating infections, but also in contributing to numerous other clinical conditions, including cardiovascular diseases and neurodegenerative disor...

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Detalles Bibliográficos
Autores principales: Faergeman, Soren L., Evans, Hayley, Attfield, Kathrine E., Desel, Christiane, Kuttikkatte, Subita Balaram, Sommerlund, Mette, Jensen, Lise Torp, Frokiaer, Jorgen, Friese, Manuel A., Matthews, Paul M., Luchtenborg, Christian, Brügger, Britta, Oturai, Annette Bang, Dendrou, Calliope A., Fugger, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195448/
https://www.ncbi.nlm.nih.gov/pubmed/32358523
http://dx.doi.org/10.1038/s41419-020-2494-0

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