Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism

The trans-synaptic interaction of the cell-adhesion molecules teneurins (TENs) with latrophilins (LPHNs/ADGRLs) promotes excitatory synapse formation when LPHNs simultaneously interact with FLRTs. Insertion of a short alternatively-spliced region within TENs abolishes the TEN-LPHN interaction and sw...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jingxian, Xie, Yuan, Cornelius, Shaleeka, Jiang, Xian, Sando, Richard, Kordon, Szymon P., Pan, Man, Leon, Katherine, Südhof, Thomas C., Zhao, Minglei, Araç, Demet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195488/
https://www.ncbi.nlm.nih.gov/pubmed/32358586
http://dx.doi.org/10.1038/s41467-020-16029-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195488/
https://www.ncbi.nlm.nih.gov/pubmed/32358586
http://dx.doi.org/10.1038/s41467-020-16029-7

Ejemplares similares