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Essential thrombocythemia manifesting as ophthalmic artery occlusion
PURPOSE: To report the first case of a patient with essential thrombocythemia (ET) who presented with unilaterally extensive choroidal ischemia coinciding with central retinal artery occlusion (CRAO). Observations: A 64-year-old man presented with a classic sign of short posterior ciliary artery (SP...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195516/ https://www.ncbi.nlm.nih.gov/pubmed/32373760 http://dx.doi.org/10.1016/j.ajoc.2020.100724 |
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author | Thabsuwan, Kittipong Chantarasorn, Yodpong |
author_facet | Thabsuwan, Kittipong Chantarasorn, Yodpong |
author_sort | Thabsuwan, Kittipong |
collection | PubMed |
description | PURPOSE: To report the first case of a patient with essential thrombocythemia (ET) who presented with unilaterally extensive choroidal ischemia coinciding with central retinal artery occlusion (CRAO). Observations: A 64-year-old man presented with a classic sign of short posterior ciliary artery (SPCA) occlusion, Amalric triangular choroidal infarction, coinciding with CRAO in the left eye. He was later diagnosed as having ET due to a massive platelet count of 1,100,000 cells/mm(3) and confirmed genetic testing. The magnetic resonance angiogram subsequently revealed severe occlusions of neuro-ophthalmic circulation. Interestingly, occult choriocapillaris occlusions were detected in the right eye despite being visually asymptomatic. CONCLUSION AND IMPORTANCE: Patients with ET can present with concurrent CRAO and SPCA occlusion. Identifying the causes of such events is crucial as these can precede systemic thrombocytosis or hemorrhagic complications. |
format | Online Article Text |
id | pubmed-7195516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-71955162020-05-05 Essential thrombocythemia manifesting as ophthalmic artery occlusion Thabsuwan, Kittipong Chantarasorn, Yodpong Am J Ophthalmol Case Rep Case Report PURPOSE: To report the first case of a patient with essential thrombocythemia (ET) who presented with unilaterally extensive choroidal ischemia coinciding with central retinal artery occlusion (CRAO). Observations: A 64-year-old man presented with a classic sign of short posterior ciliary artery (SPCA) occlusion, Amalric triangular choroidal infarction, coinciding with CRAO in the left eye. He was later diagnosed as having ET due to a massive platelet count of 1,100,000 cells/mm(3) and confirmed genetic testing. The magnetic resonance angiogram subsequently revealed severe occlusions of neuro-ophthalmic circulation. Interestingly, occult choriocapillaris occlusions were detected in the right eye despite being visually asymptomatic. CONCLUSION AND IMPORTANCE: Patients with ET can present with concurrent CRAO and SPCA occlusion. Identifying the causes of such events is crucial as these can precede systemic thrombocytosis or hemorrhagic complications. Elsevier 2020-04-23 /pmc/articles/PMC7195516/ /pubmed/32373760 http://dx.doi.org/10.1016/j.ajoc.2020.100724 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Thabsuwan, Kittipong Chantarasorn, Yodpong Essential thrombocythemia manifesting as ophthalmic artery occlusion |
title | Essential thrombocythemia manifesting as ophthalmic artery occlusion |
title_full | Essential thrombocythemia manifesting as ophthalmic artery occlusion |
title_fullStr | Essential thrombocythemia manifesting as ophthalmic artery occlusion |
title_full_unstemmed | Essential thrombocythemia manifesting as ophthalmic artery occlusion |
title_short | Essential thrombocythemia manifesting as ophthalmic artery occlusion |
title_sort | essential thrombocythemia manifesting as ophthalmic artery occlusion |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195516/ https://www.ncbi.nlm.nih.gov/pubmed/32373760 http://dx.doi.org/10.1016/j.ajoc.2020.100724 |
work_keys_str_mv | AT thabsuwankittipong essentialthrombocythemiamanifestingasophthalmicarteryocclusion AT chantarasornyodpong essentialthrombocythemiamanifestingasophthalmicarteryocclusion |