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Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro–American genetic background confers optimal vaccine potential

BACKGROUND: Human tuberculosis (TB) is caused by a plethora of Mycobacterium tuberculosis complex (MTBC) strains belonging to seven phylogenetic branches. Lineages 2, 3 and 4 are considered “modern” branches of the MTBC responsible for the majority of worldwide TB. Since the current BCG vaccine conf...

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Detalles Bibliográficos
Autores principales:	Pérez, Irene, Uranga, Santiago, Sayes, Fadel, Frigui, Wafa, Samper, Sofía, Arbués, Ainhoa, Aguiló, Nacho, Brosch, Roland, Martín, Carlos, Gonzalo-Asensio, Jesús
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195525/ https://www.ncbi.nlm.nih.gov/pubmed/32361249 http://dx.doi.org/10.1016/j.ebiom.2020.102761

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