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Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment
BACKGROUND: Studying within-host genetic diversity of Mycobacterium tuberculosis (Mtb) in patients during treatment may identify adaptations to antibiotic and immune pressure. Understanding the significance of genetic heteroresistance, and more specifically heterozygous resistance-associated variant...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195533/ https://www.ncbi.nlm.nih.gov/pubmed/32361247 http://dx.doi.org/10.1016/j.ebiom.2020.102747 |