Stem-leaf saponins from Panax notoginseng counteract aberrant autophagy and apoptosis in hippocampal neurons of mice with cognitive impairment induced by sleep deprivation

BACKGROUD: Sleep deprivation (SD) impairs learning and memory by inhibiting hippocampal functioning at molecular and cellular levels. Abnormal autophagy and apoptosis are closely associated with neurodegeneration in the central nervous system. This study is aimed to explore the alleviative effect an...

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Detalles Bibliográficos
Autores principales: Cao, Yin, Yang, Yingbo, Wu, Hui, Lu, Yi, Wu, Shuang, Liu, Lulu, Wang, Changhong, Huang, Fei, Shi, Hailian, Zhang, Beibei, Wu, Xiaojun, Wang, Zhengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Pharmacology and physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195596/
https://www.ncbi.nlm.nih.gov/pubmed/32372866
http://dx.doi.org/10.1016/j.jgr.2019.01.009

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