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Prolonged astrocyte-derived erythropoietin expression attenuates neuronal damage under hypothermic conditions

BACKGROUND: Hypoxic-ischemic encephalopathy (HIE) has a high morbidity rate and involves severe neurologic deficits, including cerebral palsy. Therapeutic hypothermia (TH) has been shown to decrease the mortality rate and provide neuroprotection in infants with HIE. However, death and disability rat...

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Detalles Bibliográficos
Autores principales: Toriuchi, Kohki, Kakita, Hiroki, Tamura, Tetsuya, Takeshita, Satoru, Yamada, Yasumasa, Aoyama, Mineyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195727/
https://www.ncbi.nlm.nih.gov/pubmed/32359362
http://dx.doi.org/10.1186/s12974-020-01831-3