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The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapy

Immune checkpoint inhibitors (ICIs), such as PD-1/PD-L1 antibodies (Abs) and anti-cytotoxic T lymphocyte antigen 4 (CTLA-4) Abs, are effective for patients with various cancers. However, low response rates to ICI monotherapies and even hyperprogressive disease (HPD) have limited the clinical applica...

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Detalles Bibliográficos
Autores principales:	Wang, Xueping, Wang, Fang, Zhong, Mengjun, Yarden, Yosef, Fu, Liwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195736/ https://www.ncbi.nlm.nih.gov/pubmed/32359357 http://dx.doi.org/10.1186/s12943-020-01200-x

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