Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain

The autoinhibited Parkin catalytic domain (PDB ID: 4BM9) receptor has been described to have a role in the ubiquitination of α-syn in Parkinson's disease. Therefore, it is of interest to discuss the molecular docking analysis data of phytochemicals from ethanolic extract of Crescentia cujete wi...

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Autores principales: Anitha, P, Kumar, Praveen K, Shanmughavel, P, Nazeema, TH, Lalitha, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Research-Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196166/
https://www.ncbi.nlm.nih.gov/pubmed/32405172
http://dx.doi.org/10.6026/97320630016189
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author Anitha, P
Kumar, Praveen K
Shanmughavel, P
Nazeema, TH
Lalitha, G
author_facet Anitha, P
Kumar, Praveen K
Shanmughavel, P
Nazeema, TH
Lalitha, G
author_sort Anitha, P
collection PubMed
description The autoinhibited Parkin catalytic domain (PDB ID: 4BM9) receptor has been described to have a role in the ubiquitination of α-syn in Parkinson's disease. Therefore, it is of interest to discuss the molecular docking analysis data of phytochemicals from ethanolic extract of Crescentia cujete with the auto inhibited Parkin catalytic domain. We report the docking features of the phytochemical named 1, 2-Ethanediamine, N-(2-aminoethyl) with the target protein for further consideration towards the design and development of anti-Parkinson agents.
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spelling pubmed-71961662020-05-13 Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain Anitha, P Kumar, Praveen K Shanmughavel, P Nazeema, TH Lalitha, G Bioinformation Research-Article The autoinhibited Parkin catalytic domain (PDB ID: 4BM9) receptor has been described to have a role in the ubiquitination of α-syn in Parkinson's disease. Therefore, it is of interest to discuss the molecular docking analysis data of phytochemicals from ethanolic extract of Crescentia cujete with the auto inhibited Parkin catalytic domain. We report the docking features of the phytochemical named 1, 2-Ethanediamine, N-(2-aminoethyl) with the target protein for further consideration towards the design and development of anti-Parkinson agents. Biomedical Informatics 2020-02-29 /pmc/articles/PMC7196166/ /pubmed/32405172 http://dx.doi.org/10.6026/97320630016189 Text en © 2020 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research-Article
Anitha, P
Kumar, Praveen K
Shanmughavel, P
Nazeema, TH
Lalitha, G
Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain
title Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain
title_full Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain
title_fullStr Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain
title_full_unstemmed Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain
title_short Molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain
title_sort molecular docking analysis of phytochemicals from ethanolic extract of crescentia cujete with the auto inhibited parkin catalytic domain
topic Research-Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196166/
https://www.ncbi.nlm.nih.gov/pubmed/32405172
http://dx.doi.org/10.6026/97320630016189
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