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2019-nCoV - Towards a 4th generation vaccine

The first report of the unusual manifestation of pneumonia-like symptoms in Wuhan City, China was made on 31 December 2019. Within one week, the Chinese authorities reported that they had identified the causative agent as a new member of the Coronavirus family, the same family of that was responsibl...

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Autor principal: Chiappelli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196171/
https://www.ncbi.nlm.nih.gov/pubmed/32405164
http://dx.doi.org/10.6026/97320630016139
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author Chiappelli, Francesco
author_facet Chiappelli, Francesco
author_sort Chiappelli, Francesco
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description The first report of the unusual manifestation of pneumonia-like symptoms in Wuhan City, China was made on 31 December 2019. Within one week, the Chinese authorities reported that they had identified the causative agent as a new member of the Coronavirus family, the same family of that was responsible for MERS and SARS not so many years ago. The new virus was called Novel Coronavirus 2019 (2019-nCoV). Three weeks later, the World Health Organization declared that 2019-nCoV was capable of direct human-to-human transmission, the virus had spread across several countries in three continents, and had infected close to two thousand people, of whom at least 1 in 5 quite severely. The number of fatalities was fast rising. Yet, the World Health Organization officially announced that there is still at present no recommended anti-nCoV vaccine for subject at-risk, nor treatment for patients with suspected or confirmed nCoV, let alone 2019-nCov. It is therefore timely and critical to propose new possible and practical approaches for preventive interventions for subjects at-risk, and for treatment of patients afflicted with 2019-nCov-induced disease (Corona Virus Disease 2019; COVID-19) before the present situation explodes into a worldwide pandemic. One such potential clinical protocol is proposed as a hypothesis.
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spelling pubmed-71961712020-05-13 2019-nCoV - Towards a 4th generation vaccine Chiappelli, Francesco Bioinformation Editorial The first report of the unusual manifestation of pneumonia-like symptoms in Wuhan City, China was made on 31 December 2019. Within one week, the Chinese authorities reported that they had identified the causative agent as a new member of the Coronavirus family, the same family of that was responsible for MERS and SARS not so many years ago. The new virus was called Novel Coronavirus 2019 (2019-nCoV). Three weeks later, the World Health Organization declared that 2019-nCoV was capable of direct human-to-human transmission, the virus had spread across several countries in three continents, and had infected close to two thousand people, of whom at least 1 in 5 quite severely. The number of fatalities was fast rising. Yet, the World Health Organization officially announced that there is still at present no recommended anti-nCoV vaccine for subject at-risk, nor treatment for patients with suspected or confirmed nCoV, let alone 2019-nCov. It is therefore timely and critical to propose new possible and practical approaches for preventive interventions for subjects at-risk, and for treatment of patients afflicted with 2019-nCov-induced disease (Corona Virus Disease 2019; COVID-19) before the present situation explodes into a worldwide pandemic. One such potential clinical protocol is proposed as a hypothesis. Biomedical Informatics 2020-02-12 /pmc/articles/PMC7196171/ /pubmed/32405164 http://dx.doi.org/10.6026/97320630016139 Text en © 2020 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Editorial
Chiappelli, Francesco
2019-nCoV - Towards a 4th generation vaccine
title 2019-nCoV - Towards a 4th generation vaccine
title_full 2019-nCoV - Towards a 4th generation vaccine
title_fullStr 2019-nCoV - Towards a 4th generation vaccine
title_full_unstemmed 2019-nCoV - Towards a 4th generation vaccine
title_short 2019-nCoV - Towards a 4th generation vaccine
title_sort 2019-ncov - towards a 4th generation vaccine
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196171/
https://www.ncbi.nlm.nih.gov/pubmed/32405164
http://dx.doi.org/10.6026/97320630016139
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