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An Oncolytic Vaccinia Virus Armed with GM-CSF and IL-24 Double Genes for Cancer Targeted Therapy
PURPOSE: Targeted oncolytic vaccinia virus is an attractive candidate for cancer therapy due to its replication causing lysis of infected tumor cells as well as a delivery vector to overexpress therapeutic transgenes. This study constructed a novel oncolytic vaccinia virus carrying granulocyte-macro...
Autores principales: | Deng, Lili, Yang, Xue, Fan, Jun, Ding, Yuedi, Peng, Ying, Xu, Dong, Huang, Biao, Hu, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196195/ https://www.ncbi.nlm.nih.gov/pubmed/32425553 http://dx.doi.org/10.2147/OTT.S249816 |
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