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Proper mechanical stress promotes femoral head recovery from steroid-induced osteonecrosis in rats through the OPG/RANK/RANKL system

BACKGROUND: Long-term use of steroid may lead to osteonecrosis of the femoral head (ONFH). Mechanical stress may help bone formation and remodeling. This study aimed to probe the role of mechanical stress in the femoral head recovery in rats. METHODS: Rat models with ONFH were induced by steroid. Ra...

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Detalles Bibliográficos
Autores principales: Fu, Dapeng, Qin, Kairong, Yang, Sheng, Lu, Jianmin, Lian, Haoyi, Zhao, Dewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196225/
https://www.ncbi.nlm.nih.gov/pubmed/32359349
http://dx.doi.org/10.1186/s12891-020-03301-6