Heritable modifiers of the tumor microenvironment influence nanoparticle uptake, distribution and response to photothermal therapy

We report the impact of notch-DLL4-based hereditary vascular heterogeneities on the enhanced permeation and retention (EPR) effect and plasmonic photothermal therapy response in tumors. Methods: We generated two consomic rat strains with differing DLL4 expression on 3(rd) chromosome. These strains w...

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Detalles Bibliográficos
Autores principales: Sharma, Gayatri, Jagtap, Jaidip M., Parchur, Abdul K., Gogineni, Venkateswara R., Ran, Sophia, Bergom, Carmen, White, Sarah B., Flister, Michael J., Joshi, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196309/
https://www.ncbi.nlm.nih.gov/pubmed/32373218
http://dx.doi.org/10.7150/thno.41171

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