Cargando…
The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease
BACKGROUND: Relaxin/relaxin family peptide receptor 1 (RXFP1) signaling is important for both normal physiology and disease. Strong preclinical evidence supports relaxin as a potent antifibrotic molecule. However, relaxin‐based therapy failed in clinical trial in patients with systemic sclerosis. We...
Autores principales: | Chen, Ting‐Yun, Li, Xiaoyun, Hung, Ching‐Hsia, Bahudhanapati, Harinath, Tan, Jiangning, Kass, Daniel J., Zhang, Yingze |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196478/ https://www.ncbi.nlm.nih.gov/pubmed/32100955 http://dx.doi.org/10.1002/mgg3.1194 |
Ejemplares similares
-
Identification of a distal RXFP1 gene enhancer with differential activity in fibrotic lung fibroblasts involving AP-1
por: Chen, Ting-Yun, et al.
Publicado: (2021) -
Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat
por: Filonzi, Marcelo, et al.
Publicado: (2007) -
Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4)
por: Chen, Yan, et al.
Publicado: (2023) -
Relaxin Receptor RXFP1 and RXFP2 Expression in Ligament, Tendon, and Shoulder Joint Capsule of Rats
por: Kim, Jae Hyung, et al.
Publicado: (2016) -
The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1
por: Sethi, Ashish, et al.
Publicado: (2016)